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  • 16

    2020-02

    Why the sequence con

    In general, when biotin is linked in the peptide sequence, it is positive for biotin detection. However, due to the sequence of some products, although biotin has been connected, the biotin test is still negative.

  • 16

    2020-02

    Screening and optimization of polypeptide I

    Small molecular active peptides as vaccines, diagnostic reagents, drugs and drug lead compounds have become a new trend in the field of drug research. There are many screening methods for small molecule active peptides: phage display peptide library, rand

  • 16

    2020-02

    Peptide screening and optimization II

    For the selected peptide sequence, we can scan the random peptide library at multiple points, optimize the peptide sequence, and select the more active peptide sequence. The design of unit point scanning matrix is simple. A selected region or site of p

  • 16

    2020-02

    How to choose the purity of polypeptide

    Generally speaking, the same sequence and the same number of peptides will have different prices because of their purity. The higher the purity is, the higher the price of peptide per unit mass is. Our company can provide different purity levels for cu

  • 16

    2020-02

    Determination of polypeptide purity

    The purity of peptide is determined by UV absorption of peptide bond in target peptide by HPLC. Water and residual salts cannot be determined by UV detector. The main impurities include: incomplete sequence peptide (short peptide with one or more amino ac

  • 16

    2020-02

    What is net peptide content

    Net peptide content and peptide purity are different concepts. Net peptide content is the percentage of peptide relative to non peptide substances, most of equilibrium ions and water. Generally, hydrophilic peptides can absorb small molecules of water eve

  • 16

    2020-02

    Whether it can predict the solubility of polypeptide

    The solubility of most peptides can be predicted according to their sequences, and it is difficult to judge the solubility of some peptides, which needs to be confirmed by experiments. When you design the sequence, we can give you suggestions, so that you

  • 16

    2020-02

    Whether it can predict the difficulty of peptide production

    The difficulty of peptide production is directly related to its designed sequence, and our technicians can predict it accurately. If the designed sequence is difficult in production, it will not only affect the experimental progress, sometimes even if the

  • 16

    2020-02

    Why N-terminal acetylation and C-terminal amidation

    Chemically synthesized peptides often carry free amino and free carboxyl groups. The peptide sequence often represents the sequence of the mother protein. In order to be closer to the mother protein, the end of the peptide often needs to be closed, that i

  • 16

    2020-02

    Stability and preservation of polypeptide

    The stability of polypeptide products is not only related to the sequence of polypeptide, but also depends on the production process to a great extent. The stability of products obtained by different processes is very different, especially the sequence co

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